Place of Origin:
Anhui, China
Brand Name:
Wayeal
Certification:
ISO, CE
Model Number:
IC6200
Technical Datas of Ion Chromatography Instrument
| Product Name | IC6200 Ion Chromatography Instrument |
| System Parameters | |
| Qualitative repeatability | ≤0.5% |
| Quantitative repeatability | ≤1.0% |
| Pump System | |
| Pump material | PEEK |
| Pump flow rate | (0.001~10.000) mL/min |
| Pump head pressure resistance | (0 ~ 35) MPa |
| Flow rate setting inaccuracy | <0.1% |
| Flow stability | <0.1% |
| Pressure display accuracy | 0.01Mpa |
| Pressure pulsation | <0.5% |
| Conductivity Detector | |
| Baseline noise | ≤0.1%FS |
| Baseline drift | ≤0.5%FS |
| Minimum detectable concentration (Cl) | ≤ 0.0002ug/mL |
| Minimum detection concentration (Li) | ≤ 0.0001ug/mL |
| Conductivity cell volume | ≤ 0.6μL |
| Conductivity detection range | 0-15000μS/cm |
| Detector resolution | 0.00238nS/cm |
| Conductivity cell temperature setting error | ±0.01°C |
| Suppressor | |
| Constant current source range | 0~500mA in 0.1mA increments |
| Column Oven | |
| Temperature range | room temperature: +5°C~85°C |
| Control temperature stability | ≤ 0.1°C |
| Autosampler | |
| Injection Bits | 48/120 |
| Refrigeration temperature range | 4-30°C |
| Repeatability |
Full loop injection < 0.3% RSD, Partial injection < 0.5% RSD, Non-destructive injection < 1 % RSD (injection volume > 5uL) |
| Linearity | >0.999 |
| Cross-contamination | <0.01% |
| Eluent Generator | |
| Flow rate range | 0.001~3.000mL/min |
| Software | Self-developed SmartLab |
Performance of Ion Chromatography Instrument
1. Liquid leakage alarm
2. Automatic range detector
3. Peristaltic pump post-pump cleaning function
4. High resolution 10-inch touch screen
5. Simple piping layout
6. Consumables ID identification and life monitoring
7. High-pressure flow path automatic emptying, reducing the manual operation of the experimenter.
Application of Ion chromatography Instrument in the Pharmaceutical Industry
1. Active Pharmaceutical Ingredient (API) Analysis
Counterion Analysis: Many APIs are synthesized as salts to improve solubility, stability, or bioavailability. IC is used to quantify counterions such as chloride, sulfate, phosphate, and sodium, ensuring the correct stoichiometry of the drug substance.
Ionic Impurities: IC helps detect and quantify ionic impurities in APIs, which can arise from raw materials, synthesis processes, or degradation. Examples include halides (e.g., bromide, iodide) and sulfates.
2. Excipient Analysis
Ionic Excipients: Excipients such as buffers, stabilizers, and preservatives often contain ionic components (e.g., citrate, acetate, phosphate). IC is used to quantify these ions to ensure proper formulation and stability.
Impurity Profiling: IC can detect trace levels of ionic impurities in excipients, which could affect drug efficacy or safety.
3. Drug Product Analysis
Formulation Analysis: IC is used to analyze the ionic composition of drug formulations, including oral solutions, injectables, and topical products. This ensures the correct concentration of active and inactive ingredients.
Preservative Analysis: IC quantifies preservatives such as benzoates, sorbates, and parabens in drug products to ensure they are within acceptable limits.
Buffer Systems: IC is used to monitor buffer systems (e.g., phosphate, acetate, citrate) in liquid formulations, ensuring proper pH control and stability.
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