Place of Origin:
Anhui, China
Brand Name:
Wayeal
Certification:
CE
Model Number:
TQ9200
Technical Parameters of TQ9200
Working conditions |
|
Working power supply |
220V±22V, 50Hz±0.5Hz |
Ambient temperature |
15-30°C |
Relative humidity |
not more than 80% |
UHPLC |
|
Pump drive mode |
linear motor pump |
Gradient mode |
binary (4-waysolvent) |
Flow rate setting range |
0.001-2.000mL/min |
Flow rate setting increment |
0.001mL/min |
Maximumoperating pressure |
150MPa |
Degassing |
5-channel online degassing |
Autosampler |
|
Maximumwithstand pressure |
150MPa |
Sampling volume range |
0.1-20.0μL (50μL optional) |
Linearity |
R≥0.9999 |
Cross-contamination |
<0.004 % |
Number of samples |
108 (2*54,2 ml), supports 96 shallow well plate, 96 deep well plate, 384 well plate |
Temperature setting range |
4.0~40.0 ℃ (optional refrigeration) |
Temperature stability |
±2 ℃ |
Feed rate |
12s |
Column temperaturechamber |
|
Temperature setting range |
20.0-90.0 ℃ |
Temperature stability |
±0.02 ℃/h |
Temperature setting value error |
± 0.1 ℃ |
Triple quadrupole mass spectrometer |
|
Mass analysis range |
5-1250 |
Scanning speed |
12000 Da/s |
Mass resolution |
0.6-0.8 Da (609 mass peaks) |
Linearity range |
≥1E4 |
Mass accuracy |
0.1 Da |
Massstability |
0.1 Da/24h |
Limit of detection (rifampicin) |
0.1pg |
Sensitivity |
S:N >20w:1 on a 1pg Risperdal column |
System indicators |
|
Qualitative reproducibility |
RSD≤5% |
Quantitative reproducibility |
RSD≤5% |
Applications of LCMS
Liquid Chromatography-Mass Spectrometry (LC-MS) combines the high separation capability of liquid chromatography with the high sensitivity and specificity of mass spectrometry, making it widely applicable for the detection of complex substances across multiple industries. There are its primary application areas:
Pharmaceutical Industry
1. Drug Development & Metabolism Studies
Qualitative and quantitative analysis of small-molecule drugs (e.g., antibiotics, anticancer agents).
Identification of drug metabolites (e.g., in plasma, urine).
Analysis of biologics (peptides, proteins, antibody drugs).
2. Clinical Testing
Therapeutic Drug Monitoring (TDM, e.g., immunosuppressants, antiepileptics).
Drug abuse screening (e.g., opioids, synthetic drugs).
Hormone analysis (e.g., cortisol, sex hormones).
Life Sciences & Biotechnology
1. Proteomics & Metabolomics
Protein identification & post-translational modifications (e.g., phosphorylation, glycosylation).
Metabolite profiling (e.g., amino acids, lipids, carbohydrates).
2. Biomarker Discovery
Disease-related metabolites (e.g., cancer biomarkers, cardiovascular markers).
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